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Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 star property

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Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

1 bedroom, in-room safe, desk, laptop workspace
Lobby sitting area
Free daily buffet breakfast
Lobby sitting area
Business centre

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free Wi-Fi
  • Air-conditioning
  • Gym
  • Business services
  • Laundry room

Explore the area

View in a map
601 Main St, Buffalo, NY, 14203
  • Place, Shea's Performing Arts Center
    ‪2 min walk‬
  • Place, Buffalo Niagara Convention Center
    ‪6 min walk‬
  • Place, Niagara Square
    ‪8 min walk‬
  • Airport, Buffalo, NY (BUF-Buffalo Niagara Intl.)
    ‪22 min drive‬

Room options

View all photos for Standard Room

Standard Room | 1 bedroom, in-room safe, desk, laptop workspace

Standard Room

9.2 out of 10
Wonderful
(26 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom

Suite, 1 Bedroom | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom

8.8 out of 10
Excellent
(51 reviews)
  • City view
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

Combined shower/bathtub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

Combined shower/bathtub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed

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  • Free Wi-Fi
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The price is CHF 120
includes taxes & fees
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About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

This smoke-free hotel features a fitness centre, a business centre and dry cleaning. Free buffet breakfast and free WiFi in public areas are also provided. Additionally, laundry facilities, a 24-hour front desk and express check-out are on-site.
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers 146 accommodations with a safe and coffee/tea makers. This accommodation has separate sitting areas and is furnished with double sofa beds. Cable televisions are provided. Guests can make use of the in-room fridges and microwaves. Bathrooms include a combined bath/shower unit, complimentary toiletries and hairdryers.

This Buffalo hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and telephones; free local calls are provided (restrictions may apply). Additionally, rooms include an iron/ironing board and blackout curtains. Housekeeping is provided on a daily basis.

Recreational amenities at the hotel include a fitness centre.
Our customers tell us that they can't get enough of the helpful staff at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG. During your stay, you're just a quick walk from Market Arcade Building. Features include free breakfast and free WiFi in public areas, plus a gym.
  • Free buffet breakfast served daily
  • Free WiFi
  • Amenities include a front desk safe, a business centre and laundry facilities
  • On-site recreation includes a gym
  • Guests have great things to say about the clean guestrooms and the helpful staff
  • Steps from Market Arcade Building and Buffalo Music Hall of Fame
Public spaces have free WiFi. You'll find a business centre on site. Free breakfast is available daily. A fitness centre, a vending machine, and laundry facilities are also featured at the business-friendly Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG.

This Buffalo hotel is smoke free.

Guests are served a free buffet breakfast daily from 6:00 AM to 10:00 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Family friendly

  • In-room cot
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Conveniences

  • 24-hour front desk
  • Guidebooks
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Lift
  • Low-height electrical sockets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business centre
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

More

  • 7 floors
  • At least 80% lighting from LEDs
  • Comprehensive food waste policy
  • Eco-friendly cleaning products used
  • Smoke-free property
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free cot

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 49-inch TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; check-in end time: anytime
Contactless check-in and check-out are available
Minimum check-in age - 21

Check-out

Check-out before 11 AM
Contactless check-out
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed, but service animals are welcome

Children and extra beds

  • Children are welcome.
  • Kids stay free! Children 18 years old and younger stay free when using existing bedding.
  • Rollaway/extra beds are not available.
  • Free cots (infant beds)!

Payment types at the property

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Nearby parking fee: USD 16.00 per day (500 ft away)

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property uses eco-friendly cleaning products
Safety features at this property include a fire extinguisher, a smoke detector and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
Front desk staff will greet guests on arrival at the property.

We should mention

  • Children aged 18 years old and younger stay free in the same room as the parent or guardian when using existing bedding.
  • Registered guests are the only ones allowed to be in guestrooms.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Buffalo Downtown Hotel
Comfort Suites Hotel Downtown
Comfort Suites Downtown Hotel Buffalo
Comfort Suites Downtown Buffalo
Comfort Suites Downtown Buffalo Hotel
Comfort Suites Buffalo
Buffalo Comfort Suites
Holiday Inn Express Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown Medical CTR
Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

Reviews

8.6

Excellent

Rating 10 - Excellent. 564 out of 1005 reviews
Rating 8 - Good. 273 out of 1005 reviews
Rating 6 - Okay. 74 out of 1005 reviews
Rating 4 - Poor. 41 out of 1005 reviews
Rating 2 - Terrible. 53 out of 1005 reviews

8.8/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.6/10

Property conditions & facilities

Reviews

2/10 Terrible

MASAHIRO

Business traveller
Liked: Cleanliness, amenities, property conditions & facilities
When I checked out, I paid for my stay with a credit card at the front desk, but requested a receipt, which was refused. I was on a business trip, but without a receipt, I cannot settle the expenses. The hotel must immediately send me a receipt by email. If they refuse, I will not hesitate to sue them.
Stayed 3 nights in Feb 2026

4/10 Poor

Justin

Travelled with partner
Room was dark. Fire alarm went off at 5 am.
Stayed 1 night in Feb 2026

4/10 Poor

Robert

Travelled with family, Travelled with partner
Disliked: Cleanliness, amenities, property conditions & facilities
Upon arrival the first room Ingotnto had not been cleaned or serviced. When I notified the front deak she told me thats why she doesnt like checking people in early with a clear attititude. The overall appearance and cleanliness of the hotel was sub par, even by holiday inn express standards.
Stayed 1 night in Jan 2026

10/10 Excellent

Eden

Liked: Cleanliness, amenities, property conditions & facilities
Very clean and friendly
Stayed 1 night in Feb 2026

2/10 Terrible

Stephanie

Disliked: Cleanliness, amenities, property conditions & facilities
Very disappointing stay. At check-in, the front desk agent was distracted and unprofessional, carrying on another conversation while helping me. The room keys didn’t work, and I had to go back and forth to the front desk multiple times, waiting in long lines each time. It took about 45 minutes just to get into my room, which made me late when I already had somewhere to be. Once inside, the room clearly wasn’t properly cleaned—there were other guests’ hair products on the floor, a hole in the door, and the toilet wouldn’t flush unless you tried several times. Overall, one of the worst hotel experiences I’ve had. Would not recommend.
Stayed 1 night in Jan 2026

4/10 Poor

Kaylee

Travelled with partner
Liked: Cleanliness
Disliked: Amenities, property conditions & facilities
Check in was terrible, keys didn’t work, staff barely batted an eye at me, rude staff, wifi was terrible, no option for early check in, parking too far away
Stayed 1 night in Jan 2026

10/10 Excellent

Theron

Big, spacious room and suite. Excellent location
Stayed 1 night in Feb 2026

8/10 Good

Jennifer

Stayed 1 night in Nov 2025

10/10 Excellent

Richard

Stayed 1 night in Feb 2026

10/10 Excellent

Bryan

Stayed 1 night in Jan 2026

10/10 Excellent

Charles

Liked: Cleanliness, property conditions & facilities
No parking is not a good thing
Stayed 1 night in Jan 2026

10/10 Excellent

Mallory

Travelled with partner
Liked: Cleanliness, property conditions & facilities
The room was great and spacious
Stayed 1 night in Jan 2026

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great service and great location
Stayed 1 night in Jan 2026

2/10 Terrible

William

Disliked: Cleanliness, staff & service, amenities
This has got to be the worst place I've ever stayed in , rude staff and no help what's o ever , I will never stay here again let alone a holiday in in the near future .. dirty room and parking is 2 blocks away
Stayed 1 night in Jan 2026

10/10 Excellent

Camryn

Stayed 1 night in Jan 2026

10/10 Excellent

Shauna

Stayed 1 night in Jan 2026

10/10 Excellent

Paul

Travelled with group
Liked: Cleanliness, amenities, property conditions & facilities
The room was clean, the staff were AMAZING, especially Mario and Eddie on the front desk!!! I cannot say how incredible the overall experience was. Would highly recommend
Stayed 1 night in Jan 2026

10/10 Excellent

Joseph

Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Great Stay All Around!!! Great Friendly Staff, Close To Everything AAAAA+++++
Stayed 1 night in Jan 2026

6/10 Okay

Patricia

Travelled with family
Liked: Cleanliness
Room noisy as we were on Main Street side with train When we went at 8a for breakfast it was wiped out
Stayed 1 night in Jan 2026

10/10 Excellent

Adam

Liked: Cleanliness, amenities, property conditions & facilities
Clean room
Stayed 1 night in Jan 2026

10/10 Excellent

RYAN

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Rooms were large. Breakfast was good and very friendly and helpful staff
Stayed 1 night in Jan 2026

10/10 Excellent

Timothy

Stayed 1 night in Jan 2026

8/10 Good

Ashley

Stayed 1 night in Jan 2026

10/10 Excellent

Rob

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
There is no on site parking. But weekends there are two side streets right at the hotel free parking on the street. We got a spot close to the front door. There are garage parking options close by. Rooms are spacious well kept and clean. Breakfast was good but since they make a bunch of food it does sit a while so pretty hard to make it all fresh. They had two different omelets. Cereals yogurt sausages and turkey sausage. Fresh cinnamon buns. Bread, muffins. Tea and coffee and white milk as well as chocolate. Plus orange and cranberry juice. So a good cariety
Nice comfy bed. Tv in here as well
Big bathroom
Sitting or work area with work setup stations and pull out couch. Tv in room
Stayed 1 night in Jan 2026

6/10 Okay

Kenneth

Travelled with family
They didnt have the pancake machine working. They also had rattling pipes in the walls all night.
Stayed 5 nights in Jan 2026