Best Hotels in Cape Girardeau County for 2026

Our customers tell us that they can't get enough of the free breakfast at Drury Plaza Hotel Cape Girardeau Conference Center. During your stay, you'll be connected to the convention centre and within walking distance of Saint Francis Medical Center. Enjoy features like free WiFi in public areas, free self-parking and a free manager's reception.

During your stay at The Riverview, you're just a quick walk from Isle Casino Cape Girardeau. Features include free WiFi in public areas and free self-parking, plus 2 restaurants.

Our customers tell us that they can't get enough of the helpful staff at Drury Inn & Suites Cape Girardeau. During your stay, you'll be within walking distance of Saint Francis Medical Center. Free breakfast, free WiFi in public areas and free self-parking are available.

Our customers tell us that they can't get enough of the helpful staff at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau. During your stay, you'll be within walking distance of Cape Girardeau Conservation Nature Center. Enjoy features like free breakfast, free WiFi in public areas and free self-parking.

Our customers tell us that they can't get enough of the helpful staff at Drury Inn & Suites Jackson MO. During your stay, you'll be close to Litz Park. Features include free breakfast, free WiFi in public areas and free self-parking.

Our customers tell us that they can't get enough of the helpful staff at Candlewood Suites Cape Girardeau by IHG. During your stay, you'll be within walking distance of Saint Francis Medical Center. Features include free WiFi in public areas and free self-parking, plus an indoor pool.

The shopping around Pear Tree Inn Cape Girardeau West gets high marks from our customers. During your stay, you'll be within walking distance of Saint Francis Medical Center. Free breakfast, free WiFi in public areas and free self-parking are available.

Our customers tell us that they can't get enough of the helpful staff at Courtyard by Marriott Cape Girardeau Downtown. During your stay, you're just a quick walk from Mississippi River. You'll find features such as free WiFi in public areas and free self-parking, plus a restaurant.

Our customers tell us that they can't get enough of the helpful staff at Pear Tree Inn Cape Girardeau Near the Medical Center. During your stay, you'll be within walking distance of Saint Francis Medical Center. You'll find features such as free WiFi in public areas.

The free breakfast at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG gets high marks from our customers. During your stay, you'll be within walking distance of Saint Francis Medical Center. You'll find features such as free WiFi in public areas and free self-parking, plus a full-service spa.

During your stay at Fairfield Inn & Suites by Marriott Cape Girardeau, you'll be within walking distance of Saint Francis Medical Center. You'll find features such as free breakfast, free WiFi in public areas and free self-parking.

Our customers tell us that they can't get enough of the helpful staff at Quality Inn Cape Girardeau North. During your stay, you'll be within walking distance of Saint Francis Healthcare System. Features include free breakfast, free WiFi in public areas and free self-parking.

Our customers tell us that they can't get enough of the helpful staff at Hampton Inn Cape Girardeau I 55 East. During your stay, you're just a quick walk from Saint Francis Medical Center. Enjoy features like free breakfast, free WiFi in public areas and free self-parking. This property offers pet-friendly amenities, such as food and water bowls.

During your stay at Tru By Hilton Cape Girardeau, you'll be within walking distance of Cape Girardeau Conservation Nature Center. Enjoy features like free breakfast and free self-parking, plus an indoor pool.

Our customers tell us that they can't get enough of the helpful staff at Town House Inn. During your stay, you'll be within walking distance of Litz Park. Enjoy features like free WiFi in public areas and free self-parking, plus laundry facilities.