South Carolina Midlands Boutique Hotels

Start date: Check-in selected.
To Date
End date: Check-out

Check availability on South Carolina Midlands Boutique Hotels

9 Dec - 10 Dec
Tonight
Check prices in South Carolina Midlands for tonight, 9 Dec - 10 Dec
10 Dec - 11 Dec
Tomorrow night
Check prices in South Carolina Midlands for tomorrow night, 10 Dec - 11 Dec

Featured South Carolina Midlands Boutique Hotels

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
The price is CHF 118 per night
CHF 118
21 Dec - 22 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Hotel Florence, Tapestry Collection by Hilton. During your stay, you're just a quick walk from Pee Dee Mental Health Center. You'll find features such as free WiFi in public areas and free self-parking, plus a full-service spa.
Wellness
Parkplatz inbegriffen
The Inn at the Crossroads

The Inn at the Crossroads

2 out of 5
128 West Main Street Lake City SC
The price is CHF 121 per night
CHF 121
18 Dec - 19 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at The Inn at the Crossroads. During your stay, you're just a quick walk from Lynches Lake Historical Society. You'll find features such as free breakfast, free WiFi in public areas and free self-parking.
Frühstück inbegriffen
Parkplatz inbegriffen
The Mantissa Hotel

The Mantissa Hotel

3 out of 5
130 East Carolina Ave Hartsville SC
The price is CHF 146 per night
CHF 146
17 Dec - 18 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at The Mantissa Hotel. During your stay, you're just a quick walk from Hartsville Museum. You'll find features such as free breakfast, free WiFi in public areas and free self-parking.
Frühstück inbegriffen
Parkplatz inbegriffen
Inn on the Square, an Ascend Collection Hotel

Inn on the Square, an Ascend Collection Hotel

3 out of 5
104 Court Avenue East Greenwood SC
The price is CHF 98 per night
CHF 98
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Inn on the Square, an Ascend Collection Hotel. During your stay, you're just a quick walk from Greenwood Museum. You'll find features such as free WiFi in public areas and free self-parking, plus a restaurant.
Parkplatz inbegriffen
Kostenloses WLAN
Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
1619 Pendleton Street Columbia SC
The price is CHF 91 per night
CHF 91
27 Dec - 28 Dec
includes taxes & fees
Our customers tell us they can't get enough of Graduate by Hilton Columbia SC's great location. During your stay, you're just a quick walk from Town Theatre. Enjoy features like free WiFi in public areas, plus a restaurant and a 24-hour gym. This property offers pet-friendly amenities, such as food and water bowls.
Haustierfreundlich
Kostenloses WLAN
Hyatt Place Columbia/Downtown/The Vista

Hyatt Place Columbia/Downtown/The Vista

3 out of 5
819 Gervais Street Columbia SC
The price is CHF 99 per night
CHF 99
19 Dec - 20 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at Hyatt Place Columbia/Downtown/The Vista. During your stay, you're just a quick walk from University of South Carolina. Free WiFi in public areas, an indoor pool and a restaurant are available.
Pool
Frühstück inbegriffen
Sheraton Columbia Downtown Hotel

Sheraton Columbia Downtown Hotel

3.5 out of 5
1400 Main St Columbia SC
The price is CHF 100 per night
CHF 100
21 Dec - 22 Dec
includes taxes & fees
Sheraton Columbia Downtown Hotel's great location gets high marks from our customers. During your stay, you're just a quick walk from Soda City Market. Enjoy features like free WiFi in public areas, plus 2 bars and a 24-hour gym.
Kostenloses WLAN
Klimaanlage
Lookaway Inn

Lookaway Inn

2.5 out of 5
103 W Forest Ave North Augusta SC
Get rates
Our customers tell us that they can't get enough of the free breakfast at Lookaway Inn. During your stay, you're just a quick walk from Living History Park. Free WiFi in public areas and free self-parking are available.
Frühstück inbegriffen
Parkplatz inbegriffen
Quality Inn Kingstree

Quality Inn Kingstree

2.5 out of 5
1610 N Longstreet St Kingstree SC
The price is CHF 77 per night
CHF 77
4 Jan - 5 Jan 2026
includes taxes & fees
Features at Quality Inn Kingstree include free breakfast, WiFi in public areas and self-parking.
Frühstück inbegriffen
Haustierfreundlich
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South Carolina Midlands hotels essential information

Accommodation
3,064 hotels
Lowest Price
CHF 77
Highest Price
CHF 146
Popular hotels
Hotel Florence, Tapestry Collection by Hilton, The Inn at the Crossroads, The Mantissa Hotel, Inn on the Square, an Ascend Collection Hotel, Graduate by Hilton Columbia SC, Hyatt Place Columbia/Downtown/The Vista, Sheraton Columbia Downtown Hotel, Lookaway Inn, Quality Inn Kingstree

Other accommodation options

Areas of South Carolina Midlands