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21C Museum Hotel St Louis

4.5 star property

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Photo gallery for 21C Museum Hotel St Louis

Interior
Loft, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains
Billiards
Exterior
Dining

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Pet-friendly
  • Free Wi-Fi
  • Air-conditioning

Explore the area

View in a map
1528 Locust street, St. Louis, MO, 63103
  • Place, St. Louis Union Station
    ‪6 min walk‬
  • Place, Enterprise Center
    ‪6 min walk‬
  • Place, City Museum
    ‪6 min walk‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪19 min drive‬

Room options

View all photos for Deluxe Room, 1 King Bed

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(81 reviews)
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

Luxury Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains

Luxury Double Room, 2 Queen Beds

9.2 out of 10
Wonderful
(24 reviews)
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room (Bunk Bed)

In-room safe, desk, laptop workspace, blackout curtains

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Single Bunk Bed

View all photos for Loft, 2 Queen Beds

In-room safe, desk, laptop workspace, blackout curtains

Loft, 2 Queen Beds

8.0 out of 10
Very good
(1 review)
  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Deluxe Room, Accessible (Accessible)

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Room, Accessible (Accessible)

  • 25 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (21C)

Suite, 1 King Bed (21C) | In-room safe, desk, laptop workspace, blackout curtains

Suite, 1 King Bed (21C)

  • 104 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library) | In-room safe, desk, laptop workspace, blackout curtains

Suite, 1 King Bed (Library)

  • 68 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed | In-room safe, desk, laptop workspace, blackout curtains

Luxury Suite, 1 King Bed

10.0 out of 10
Exceptional
(1 review)
  • 51 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 Double Bed, Accessible

Deluxe Room, 1 Double Bed, Accessible | In-room safe, desk, laptop workspace, blackout curtains

Deluxe Room, 1 Double Bed, Accessible

  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Suite, 1 Double Bed, Accessible

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Suite, 1 Double Bed, Accessible

  • 48 sq m
  • Sleeps 2
  • 1 Double Bed

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About this property

21C Museum Hotel St Louis

Luxury hotel with fitness centre and steam room
This smoke-free hotel features an indoor pool, a restaurant and a fitness centre. WiFi in public areas is free. Additionally, a bar/lounge, a steam room and a coffee shop/cafe are on-site. Change of towels is available on request
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and a safe. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries and hairdryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs and telephones. Additionally, rooms include complimentary bottles of water and an iron/ironing board. Change of towels and change of bedsheets can be requested. Housekeeping is provided on a daily basis.

Recreational amenities at the hotel include an indoor pool, a steam room and a fitness centre.
Guests can pamper themselves by indulging in the on-site spa services. Services include massages.
Our customers tell us they can't get enough of 21C Museum Hotel St Louis 's great location. During your stay, you're just a quick walk from City Museum. Enjoy features like free WiFi in public areas, plus an indoor pool and a restaurant.
  • Free WiFi
  • Drinking and dining options include a coffee shop, a restaurant and a bar/lounge
  • Cooked-to-order breakfast served daily for a fee
  • Valet parking available for a fee
  • Take a swim in the indoor pool
  • Services include dry cleaning/laundry, a concierge and luggage storage
  • On-site recreation includes a gym and a steam room
  • Guests have great things to say about the helpful staff and the location
  • Within a 10-minute walk of City Museum and Enterprise Center
  • Dogs welcome for a fee
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness centre. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business centre and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

For a fee, guests can enjoy a cooked-to-order breakfast daily from 6:30 AM to 1:00 PM.
21C Museum Hotel St Louis has a restaurant on site.
Room service (during limited hours) is available.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)
  • Limited on-site valet parking

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
    • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types at the property

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Front desk staff will greet guests on arrival at the property.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 1097 out of 1529 reviews
Rating 8 - Good. 230 out of 1529 reviews
Rating 6 - Okay. 101 out of 1529 reviews
Rating 4 - Poor. 47 out of 1529 reviews
Rating 2 - Terrible. 54 out of 1529 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Sara

Stayed 1 night in Oct 2025

10/10 Excellent

Anne

Travelled with family
Liked: Cleanliness, staff & service, amenities
Excellent staff
Stayed 3 nights in Oct 2025

10/10 Excellent

Kathleen

Stayed 1 night in Sep 2025

2/10 Terrible

Paul

Stayed 2 nights in Oct 2025

10/10 Excellent

Ana

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great customer service !
Stayed 1 night in Oct 2025

6/10 Okay

Kayla

Stayed 2 nights in Sep 2025

8/10 Good

Lisa

Liked: Cleanliness, staff & service, room comfort
Hotel itself was amazing. Had a little issues with the room. But the manger stepped up to assist to make everything better
Stayed 2 nights in Sep 2025

10/10 Excellent

Sarah

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Love the pool, spa area and the art work. We stay here often And love coming back. Great outdoor space to have a cocktail from the full bar , shuffle board , pool table and awesome mingling spaces for friends
Stayed 1 night in Sep 2025

10/10 Excellent

Angella

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

That tub though!

The hotel was beautiful. The room was so nice. That tub though, that was the highlight of my stay. The soaked tub was worth every penny.
Stayed 1 night in Sep 2025

8/10 Good

Rohat

Travelled with family, Business traveller
Liked: Staff & service, amenities, property conditions & facilities
Staff and hotel were great, area is kind of dangerous, lot's of homeless people hanging around, parking is either pay to valet for street parking or park yourself? Experience within hotel was great.
Stayed 2 nights in Jul 2025

10/10 Excellent

Jake

Stayed 1 night in Sep 2025

10/10 Excellent

ANDREA Nicole

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Top notch all the way. Absolutely love these hotels!
Stayed 2 nights in May 2025

10/10 Excellent

Latisha

Liked: Cleanliness
Stayed 1 night in Sep 2025

8/10 Good

Jane

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025

2/10 Terrible

John

Disliked: Cleanliness, staff & service, property conditions & facilities, room comfort

Common Areas Are Nice; Hotel Not Worth Your Time

I wanted to like the 21c Museum Hotel St. Louis, but my stay was disappointing from start to finish. I was moved twice; the first room had a bathroom issue; the second (promised as the same type) was noticeably smaller. I was then placed in a suite that had a strong, unpleasant odor, which I tolerated only because I was exhausted from the room changes. Common areas didn’t help: elevators were not clean, and despite requesting service, housekeeping didn’t arrive until almost 7pm. While the bar staff and one front-desk attendant were friendly, several others were curt and unhelpful. Most concerning, a staff member, likely maintenance, tried to enter my room before checkout without knocking and offered only a half-hearted apology when he saw me. I was told the first night would be refunded, but Hotels.com had no record of a refund request from the property. I had planned to return for Thanksgiving and had already booked, but I’ve since canceled. Overall, this was a poor experience marked by inconsistent service, cleanliness issues, and a lack of accountability.
Stayed 3 nights in Sep 2025

6/10 Okay

Kelly

Liked: Staff & service

Beautiful design, lacking maintenance

You can tell that there was a lot of care that went into the design and creation of this hotel, but unfortunately, there has been a lack of maintenance that erodes the overall experience. The Good: - The Museum is well curated, thoughtfully presented, and inspired. We really enjoyed each exhibit. - Idol Wolf and Good Press are both high-quality restaurants, and we enjoyed the food and service at each. The portion sizes and ingredients were both above our expectations for a hotel restaurant. The Bad: - While the rooms are clean, there was a general lack of maintenance for the most basic needs for a hotel guest. For example, our shampoo and body wash were both ripped off the wall, and rather than being repaired, the broken bottles were just placed in the shower. We needed to call the front desk in order to receive functioning toiletries, which was disappointing given the price of our nightly stay. - While a small detail, we were only provided one coffee cup in our room. A great coffee maker can only be enjoyed if we have a cup to drink out of, and it underlined the lack of attention to detail we had seen in other parts of our stay. - The pool and locker rooms were very poorly maintained and frankly dirty. Towels were not consistently available (only in the women's locker room), the shower grout was visibly moldy, and there was a lack of general maintenance in what clearly was a previously beautiful pool and spa area. Overall, the experience was fine, but below expectations.
Stayed 1 night in Sep 2025

10/10 Excellent

JeTaun

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
My stay was nice and comfortable. The staff was very courteous
Stayed 3 nights in Sep 2025

10/10 Excellent

martin

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025

10/10 Excellent

Connie

Travelled with group
Liked: Cleanliness, amenities, property conditions & facilities
Great place to stay. Will definitely stay here next time I’m in st. Luis
Stayed 1 night in Sep 2025

10/10 Excellent

Sabrina

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025

10/10 Excellent

Renean

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Sep 2025

10/10 Excellent

Fred

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Sep 2025

10/10 Excellent

Connie

Travelled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great experience!
Stayed 1 night in Sep 2025

10/10 Excellent

marie

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Aug 2025

2/10 Terrible

Angie

Disliked: Cleanliness, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025