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21C Museum Hotel St Louis

4.5 star property

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Photo gallery for 21C Museum Hotel St Louis

Interior
Suite, 1 King Bed (Library) | 1 bedroom, in-room safe, desk, laptop workspace
Billiards
Loft, 2 Queen Beds | 1 bedroom, in-room safe, desk, laptop workspace
Dining

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar

Explore the area

View in a map
1528 Locust street, St. Louis, MO, 63103
  • Place, St. Louis Union Station
    ‪6 min walk‬
  • Place, Enterprise Center
    ‪6 min walk‬
  • Place, Busch Stadium
    ‪14 min walk‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪21 min drive‬

Room options

View all photos for Deluxe Room, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(76 reviews)
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

Luxury Double Room, 2 Queen Beds | 1 bedroom, in-room safe, desk, laptop workspace

Luxury Double Room, 2 Queen Beds

9.2 out of 10
Wonderful
(23 reviews)
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room (Bunk Bed)

1 bedroom, in-room safe, desk, laptop workspace

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Single Bunk Bed

View all photos for Loft, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Loft, 2 Queen Beds

  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Deluxe Room, Accessible (Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, Accessible (Accessible)

  • 25 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (21C)

Suite, 1 King Bed (21C) | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed (21C)

  • 104 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library) | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed (Library)

  • 68 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed | 1 bedroom, in-room safe, desk, laptop workspace

Luxury Suite, 1 King Bed

10.0 out of 10
Exceptional
(1 review)
  • 51 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 Double Bed, Accessible

Deluxe Room, 1 Double Bed, Accessible | 1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, 1 Double Bed, Accessible

  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Suite, 1 Double Bed, Accessible

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Suite, 1 Double Bed, Accessible

  • 48 sq m
  • Sleeps 2
  • 1 Double Bed

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About this property

21C Museum Hotel St Louis

Luxury hotel with fitness centre and steam room
This smoke-free hotel features an indoor pool, a restaurant and a fitness centre. WiFi in public areas is free. Additionally, a bar/lounge, a steam room and a coffee shop/cafe are on-site. Change of towels is available on request
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and a safe. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries and hairdryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs and telephones. Additionally, rooms include complimentary bottles of water and an iron/ironing board. Change of towels and change of bedsheets can be requested. Housekeeping is provided on a daily basis.

Recreational amenities at the hotel include an indoor pool, a steam room and a fitness centre.
Guests can pamper themselves by indulging in the on-site spa services. Services include massages.
Our customers tell us they can't get enough of 21C Museum Hotel St Louis 's great location. During your stay, you're just a quick walk from City Museum. Enjoy features like free WiFi in public areas, plus an indoor pool and a restaurant.
  • Free WiFi
  • Drinking and dining options include a coffee shop, a restaurant and a bar/lounge
  • Cooked-to-order breakfast served daily for a fee
  • Valet parking available for a fee
  • Take a swim in the indoor pool
  • Services include dry cleaning/laundry, a concierge and luggage storage
  • On-site recreation includes a gym and a steam room
  • Guests have great things to say about the helpful staff and the clean guestrooms
  • Within a 10-minute walk of City Museum and Enterprise Center
  • Dogs welcome for a fee
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness centre. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business centre and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

For a fee, guests can enjoy a cooked-to-order breakfast daily from 6:30 AM to 1:00 PM.
21C Museum Hotel St Louis has a restaurant on site.
Room service (during limited hours) is available.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
    • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types at the property

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Front desk staff will greet guests on arrival at the property.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 1031 out of 1433 reviews
Rating 8 - Good. 211 out of 1433 reviews
Rating 6 - Okay. 93 out of 1433 reviews
Rating 4 - Poor. 44 out of 1433 reviews
Rating 2 - Terrible. 54 out of 1433 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Jamie

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Jul 2025

10/10 Excellent

Frank

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great gym and pool.
Stayed 3 nights in Apr 2025

10/10 Excellent

Cynthia

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Jul 2025

4/10 Poor

Kyle

Travelled with family and small children
Liked: Property conditions & facilities
Disliked: Cleanliness, staff & service
The property was beautiful but we did not have a good experience. There were wrappers in the hallway on the 4th floor and it looked dirty. That evening an employee opened and came all the way into our room with his key card and it freaked us out, we never found out why that happened. He just ran out the door without saying anything. The next day, the fire alarms went off multiple times and we had to go down to street level and hang out in the lobby area for 45 minutes until the firefighters declared it a false alarm. We wanted to go to the bar and get some drinks, there was nobody at the hostess station so we sat down until the bartender very rudely told us we had to wait to be seated. I asked about going to the museum and I was told that it was closed due to a private event. I asked if I could go the next morning and the front desk employee told me I could go very early because they had another event the next day too. I asked if 6am would be alright and they said yes. I woke up specifically to go see the museum and the main gallery had already been closed for the event. We were also told the pool opened at 5am but my husband went down at 5:15am and it was closed. The hotel is nice but it just feels like it has some pretty big management issues. The room was nice though and the girl who did the valet parking (a young woman wearing knee braces both times we saw her) was very friendly and efficient! Coffee at the cafe spot was great as well.
Stayed 2 nights in Jul 2025

4/10 Poor

Celeste

Liked: Cleanliness, property conditions & facilities
Disliked: Staff & service
Check in was horrible. We arrived around midnight, with no reservation. Unbeknown to us, there were a few events happening that weekend and almost all hotels were booked full. We were grateful to have found this hotel. However, at check in, the
Stayed 1 night in Jul 2025

8/10 Good

Liz

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Jul 2025

10/10 Excellent

Joseph

Stayed 3 nights in Jul 2025

8/10 Good

Angela

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wonderful hotel. I always enjoying seeking out and finding a 21C. The vibe was inviting and creative. Beautiful works of art. Loved the pool and gym/sauna/steam room area. We will stay again.
Stayed 1 night in Jul 2025

10/10 Excellent

Tedtra

Stayed 1 night in Jul 2025

10/10 Excellent

Bruce

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Art Deco at its Finest

This has been one of the best hotels I've been to in several years. Beautiful and clean with the the most beautiful art work around the whole hotel and the fact that it has its own Art Gallery is absolutely amazing.
Stayed 1 night in Jul 2025

10/10 Excellent

Trenicia

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved it! No complaints
Stayed 2 nights in Jul 2025

6/10 Okay

Bill

Travelled with family
Disliked: Amenities
The property was unique, breakfast at cafe was good. The bad, the first valet was not helpful at all , the front desk people were not helpful, when we got to our rooms my room still had food in the refrigerator and it was broke. The room was extremely hot because the a/c was off . Went to take a shower that night and the shower button was broke the drain was broke . Told front desk and they didn’t seem to concerned said that they’d heard there were some issues with some rooms. Overall for the money would not stay again
Stayed 4 nights in Jul 2025

10/10 Excellent

Sean

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

10/10 Excellent

Ashley

Stayed 1 night in Jul 2025

6/10 Okay

Melissa

Travelled with family
Definitely no attention to detail with cleanliness. Robes so wrinkled and cheap looking didn’t even want to use them. Carpets stained horribly in the hallways. Bathroom not properly wiped down.
Stayed 1 night in Jul 2025

6/10 Okay

Nicole

Liked: Staff & service
Disliked: Cleanliness

Cool vibe

Cool atmosphere and vibe, however, the room was not the cleanest. Towels had stains on them, bedding as well. There were giant cobwebs in the vents and we didn't get clean towels when they cleaned the room.
Stayed 3 nights in Jul 2025

10/10 Excellent

Randall

Stayed 2 nights in Jul 2025

10/10 Excellent

Julie

Business traveller, Travelled with partner
Liked: Amenities
Everything about this hotel was magical! Food is fove star service people rooms. Saunna workout room and it's beautiful!
Stayed 2 nights in Jul 2025

10/10 Excellent

Rebecca

Travelled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Kevin was especially helpful and good to find a fellow LFC supporter !
Stayed 2 nights in Jul 2025

10/10 Excellent

Michael

Stayed 1 night in Jul 2025

10/10 Excellent

Lindsay

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Jul 2025

6/10 Okay

Randy

Stayed 3 nights in Jul 2025

10/10 Excellent

Lynne

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

10/10 Excellent

rebecca

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was a great location
Stayed 1 night in Jun 2025

10/10 Excellent

Shauna

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Jun 2025