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Cheap Flights from Santiago to Guayaquil & Flight Information
Origin airport IATA code
SCL
Destination airport IATA code
GYE
Number of flight options
1
Average flight time
5 hours 18 mins

Guayaquil Flight Information

Traveling From
Santiago
Origin Airport IATA Code
SCL
Traveling To
Guayaquil
Destination Airport IATA Code
GYE
Number of Airlines Serving
Available Airlines
Distance
Direct Flight Time
Flight Price

Need a car after flight from Santiago to Guayaquil

Place to stay after flight from Santiago to Guayaquil

Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno Guayaquil Guayas
Dieses Hotel mit Wellnessangebot bietet dir einen angenehmen Aufenthalt in Guayaquil. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
9.4/10 Exceptional! (1,006 reviews)
Todos son muy amable!

Reviewed on 12 Feb 2026

Opens in a new windowOro Verde Guayaquil
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
Dieses Hotel für Geschäftsreisende bietet dir einen angenehmen Aufenthalt in Guayaquil. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
9.2/10 Wonderful! (1,003 reviews)
We arrived at 3am to our transfer waiting for us, the staff were all friendly and attentive. The room was spacious and clean, and the bed was very comfortable.

Reviewed on 9 Feb 2026

Opens in a new windowHoliday Inn Guayaquil Airport by IHG
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Guayaquil. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
9.2/10 Wonderful! (1,001 reviews)
Staff was very friendly, food spectacular, and the infrastructure was amazing! Spa was a plus...

Reviewed on 5 Feb 2026

Opens in a new windowWyndham Guayaquil Puerto Santa Ana
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Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111 Guayaquil
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Guayaquil. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
8.6/10 Excellent! (855 reviews)
Did meet my expectation

Reviewed on 7 Feb 2026

Opens in a new windowHilton Colon Guayaquil
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 out of 5
Juan Tanca Marengo Ave Guayaquil Guayas
Dieses Hotel für Geschäftsreisende bietet dir einen angenehmen Aufenthalt in Guayaquil. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
9/10 Wonderful! (1,000 reviews)
Cold AC. Great customer service. You will find anything that you need within walking distance. Super clean room

Reviewed on 7 Feb 2026

Opens in a new windowWyndham Garden Guayaquil
TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

4.5 out of 5
Av. Joaquín Orrantia y L. Benitez Guayaquil Guayas
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Guayaquil. Freu dich auf WLAN-Internetzugang (kostenlos), 2 Restaurants und 2 Bars/Lounges. ...
8.8/10 Excellent! (1,002 reviews)
Nice and neat room, courteous staff.

Reviewed on 4 Feb 2026

Opens in a new windowTRYP by Wyndham Guayaquil Airport
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all holiday package bookings with Flight + Hotel made on ebookers.ie from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.