Find Cheap Flights from Santiago de los Caballeros (POP) to Panama City (PTY) from CHF 716

Many airlines offer flexible change policies

Earn BONUS+ rewardsOpens in a new window on top of your airline points

Enjoy exclusive promotions on the ebookers app!

Selected flight deals from Santiago de los Caballeros to Panama City

The lowest prices found within the past 7 days from Santiago de los Caballeros to Panama City were CHF 431 for one-way flights and CHF 716 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, 18 Nov - Thu, 20 Nov
STI
Cibao Intl.
PTY
Tocumen Intl.
CHF 716 Return, found 2 hours ago
CHF 716
Return
found 2 hours ago
Select American Airlines flight, departing Tue, 18 Nov from Cibao Intl. to Tocumen Intl., returning Thu, 20 Nov, priced at CHF 716 found 2 hours ago
Mon, 24 Nov - Tue, 25 Nov
STI
Cibao Intl.
PTY
Tocumen Intl.
CHF 745 Return, found 2 hours ago
CHF 745
Return
found 2 hours ago
Select American Airlines flight, departing Mon, 24 Nov from Cibao Intl. to Tocumen Intl., returning Tue, 25 Nov, priced at CHF 745 found 2 hours ago
Sun, 23 Nov - Tue, 25 Nov
STI
Cibao Intl.
PTY
Tocumen Intl.
CHF 750 Return, found 2 hours ago
CHF 750
Return
found 2 hours ago
Select American Airlines flight, departing Sun, 23 Nov from Cibao Intl. to Tocumen Intl., returning Tue, 25 Nov, priced at CHF 750 found 2 hours ago
Tue, 18 Nov - Mon, 1 Dec
STI
Cibao Intl.
PTY
Tocumen Intl.
CHF 769 Return, found 2 hours ago
CHF 769
Return
found 2 hours ago
Select American Airlines flight, departing Tue, 18 Nov from Cibao Intl. to Tocumen Intl., returning Mon, 1 Dec, priced at CHF 769 found 2 hours ago
Sat, 22 Nov - Mon, 24 Nov
STI
Cibao Intl.
PTY
Tocumen Intl.
CHF 773 Return, found 2 hours ago
CHF 773
Return
found 2 hours ago
Select American Airlines flight, departing Sat, 22 Nov from Cibao Intl. to Tocumen Intl., returning Mon, 24 Nov, priced at CHF 773 found 2 hours ago
Cheap Flights from Santiago de los Caballeros to Panama City & Flight Information
Origin airport IATA code
STI
Destination airport IATA code
PTY
Return price
CHF 715

Panama City Flight Information

Traveling From
Santiago de los Caballeros
Origin Airport IATA Code
POP
Traveling To
Panama City
Destination Airport IATA Code
PTY
Number of Airlines Serving
Available Airlines
American Airlines, United
Distance
Direct Flight Time
Flight Price
CHF 716

Need a car after flight from Santiago de los Caballeros to Panama City

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

Place to stay after flight from Santiago de los Caballeros to Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Dieses Hotel mit 5 Sternen im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Panama-Stadt. Freu dich auf inbegriffenes Frühstück, WLAN-Internetzugang ...
9/10 Wonderful! (4,370 reviews)
"good"

Reviewed on 10 Oct 2025

Opens in a new windowHotel Riu Plaza Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Dieses Resort mit 4 Sternen mit Wellnessangebot bietet dir einen angenehmen Aufenthalt in Panama-Stadt. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ...
8.4/10 Very Good! (963 reviews)
"Relaxing but close by to everything"

Reviewed on 2 Oct 2025

Opens in a new windowSheraton Grand Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
Dieses Hotel mit 4,5 Sternen im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Panama-Stadt. Freu dich auf inbegriffenes Frühstück, WLAN-Internetzugang ...
8.4/10 Very Good! (1,117 reviews)
"Best"

Reviewed on 10 Oct 2025

Opens in a new windowMegapolis Hotel Panamá
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall, Panama City, Panama
Dieses Hotel mit 4 Sternen für Geschäftsreisende bietet dir einen angenehmen Aufenthalt in Panama-Stadt. Freu dich auf WLAN-Internetzugang (kostenlos), 2 Restaurants ...
9/10 Wonderful! (1,001 reviews)
"Helpfull staff"

Reviewed on 3 Oct 2025

Opens in a new windowMarriott Panama Hotel
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina, Panama City, Panama
Dieses Hotel mit 3 Sternen für Geschäftsreisende bietet dir einen angenehmen Aufenthalt in Panama-Stadt. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ...
8.8/10 Excellent! (1,503 reviews)
"Everything was clean except for main desk. Entire desk was excessively sticky. Staff was excellent. Too many weird rules with hotel guests having visitors."

Reviewed on 8 Oct 2025

Opens in a new windowPrincipe Hotel and Suites
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street, Panama City, Panama
Dieses Hotel mit 5 Sternen im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Panama-Stadt. Freu dich auf WLAN-Internetzugang (kostenlos), Wellnessbereich ...
8.8/10 Excellent! (1,000 reviews)
"Oliver was a pleasure and very informative on the surrounding areas, include very pleasant attitude with a smile on his face daily !! Thank you Oliver !!"

Reviewed on 29 Sept 2025

Opens in a new windowWaldorf Astoria Panama
Don't see what you're looking for?
See all available properties in Panama City
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santiago de los Caballeros Airports

Panama City Airports

Other Flights to Panama City

Flights from Other Cities

Top Trending

^Savings based on all holiday package bookings with Flight + Hotel made on ebookers.ie from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.