Find Cheap Flights from Lyon (LYS) to Mainz (FRA) from CHF 272

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Selected flight deals from Lyon to Mainz

The lowest prices found within the past 7 days from Lyon to Mainz were CHF 158 for one-way flights and CHF 272 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Cheap Flights from Lyon to Mainz & Flight Information
Origin airport IATA code
LYS
Destination airport IATA code
FRA
Number of flight options
1
Return price
CHF 271
Average flight time
1 hour 23 mins

Mainz Flight Information

Traveling From
Lyon
Origin Airport IATA Code
LYS
Traveling To
Mainz
Destination Airport IATA Code
FRA
Number of Airlines Serving
Available Airlines
Air France, Brussels Airlines, Lufthansa, British Airways, KLM, Air Dolomiti
Distance
Direct Flight Time
Flight Price
CHF 272

Need a car after flight from Lyon to Mainz

Place to stay after flight from Lyon to Mainz

H2 Hotel Mainz

H2 Hotel Mainz

Rheinalle 46 Mainz
Dieses Hotel bietet dir einen angenehmen Aufenthalt in Mainz. Freu dich auf inbegriffenes Frühstück, WLAN-Internetzugang (kostenlos) und Parken ohne Service ...
9.2/10 Wonderful! (418 reviews)
Petit dejeuner parfait pour commencer la journée. La chambre était de bonne dimension. Seul point à améliorer: ajouter des crochets dans la salle d’eau pour la serviette à main et dans la salle de bain pour au moins 4 serviettes.

Reviewed on 23 Apr 2026

Opens in a new windowH2 Hotel Mainz
Holiday Inn - the niu, Mood Mainz by IHG

Holiday Inn - the niu, Mood Mainz by IHG

Mombacher Straße 6 Mainz
Dieses Hotel bietet dir einen angenehmen Aufenthalt in Mainz. Freu dich auf WLAN-Internetzugang (kostenlos), Frühstück (gegen Gebühr) und Sauna. Die Gäste loben ...
8.8/10 Excellent! (707 reviews)
Great room and clean facility

Reviewed on 15 Dec 2025

Opens in a new windowHoliday Inn - the niu, Mood Mainz by IHG
Leonardo Hotel Mainz

Leonardo Hotel Mainz

Augustusstrasse 6 Mainz RP
Dieses Hotel bietet dir einen angenehmen Aufenthalt in Mainz. Freu dich auf Frühstück (gegen Gebühr), Zimmerservice (rund um die Uhr) und Fitnessmöglichkeiten. ...
8.4/10 Very Good! (882 reviews)
No not good

Reviewed on 9 Apr 2026

Opens in a new windowLeonardo Hotel Mainz
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Hilton Mainz

Hilton Mainz

Rheinstrasse 68 Mainz
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Mainz. Freu dich auf WLAN-Internetzugang (kostenlos), Frühstück (gegen Gebühr) und ...
8.6/10 Excellent! (436 reviews)
Great breakfast selection

Reviewed on 15 Apr 2026

Opens in a new windowHilton Mainz
Atrium Hotel Mainz

Atrium Hotel Mainz

4.5 out of 5
Flugplatzstr. 44 Mainz RP
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Mainz. Freu dich auf WLAN-Internetzugang (kostenlos), Wellnessbereich und 3 Restaurants. ...
9/10 Wonderful! (392 reviews)
We stayed in the "Comfort Double Room" part of the hotel, and the place was far from 4-star superior quality. It felt like an unmaintained 1980s relic with unpleasant red shag carpet and almost zero soundproofing. The room was objectively dirty and hazardous: Hygiene: There was active mold on the ...

Reviewed on 6 Apr 2026

Opens in a new windowAtrium Hotel Mainz
Hyatt Regency Mainz

Hyatt Regency Mainz

Templerstraße 6 Mainz
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Mainz. Freu dich auf WLAN-Internetzugang (kostenlos), Wellnessbereich und Frühstück ...
9.4/10 Exceptional! (776 reviews)
The staff were very professional and polite. We had 2 rooms, and we were very pleased with the space and how comfortable the beds were. Definitely a must to visit again.

Reviewed on 26 Apr 2026

Opens in a new windowHyatt Regency Mainz
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all holiday package bookings with Flight + Hotel made on ebookers.ie from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.