Find cheap hotels in Southeast Missouri
Hotels from CHF 48
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Check hotel availability in Southeast Missouri
Most frequently booked hotels in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
61.18 km from city centre
The price is CHF 48 per night
CHF 48
3 Jan - 4 Jan 2026
includes taxes & fees
Our customers tell us that they enjoy the free breakfast at Baymont Inn and Suites by Wyndham Farmington, MO. During your stay, you'll be within walking distance of Parkland Health Center. Free WiFi in public areas, free self-parking and a 24-hour gym are available.
Pool
Frühstück inbegriffen

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
75.5 km from city centre
The price is CHF 80 per night
CHF 80
28 Dec - 29 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at Drury Plaza Hotel Cape Girardeau Conference Center. During your stay, you'll be connected to the convention centre and within walking distance of Saint Francis Medical Center. Enjoy features like free WiFi in public areas, free self-parking and a free manager's reception.
Pool
Whirlpool

The Riverview
777 Main St Cape Girardeau MO
81.09 km from city centre
The price is CHF 86 per night
CHF 86
28 Dec - 29 Dec
includes taxes & fees
During your stay at The Riverview, you're just a quick walk from Isle Casino Cape Girardeau. Features include free WiFi in public areas and free self-parking, plus 2 restaurants.
Parkplatz inbegriffen
Kostenloses WLAN

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
46.95 km from city centre
The price is CHF 63 per night
CHF 63
25 Dec - 26 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Motel 6 Poplar Bluff, MO. During your stay, you'll be close to Poplar Bluff Regional Medical Center. Features include free WiFi in public areas and free self-parking, plus laundry facilities.
Haustierfreundlich
Parkplatz inbegriffen

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
73.6 km from city centre
The price is CHF 72 per night
CHF 72
7 Jan - 8 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau. During your stay, you'll be within walking distance of Cape Girardeau Conservation Nature Center. Enjoy features like free breakfast, free WiFi in public areas and free self-parking.
Pool
Frühstück inbegriffen

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
85.38 km from city centre
The price is CHF 87 per night
CHF 87
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Hampton Inn Sikeston. During your stay, you'll be within walking distance of Central Park. Features include free breakfast, free WiFi in public areas and free self-parking.
Pool
Frühstück inbegriffen

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
1001 Veterans Blvd Festus MO
110.1 km from city centre
The price is CHF 84 per night
CHF 84
25 Dec - 26 Dec
includes taxes & fees
The free breakfast at La Quinta Inn & Suites by Wyndham Festus - St. Louis South gets good marks from our customers. During your stay, you'll be within walking distance of Jorkerst Memorial Park. Enjoy features like free WiFi in public areas and free self-parking, plus a gym.
Frühstück inbegriffen
Haustierfreundlich

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
87.14 km from city centre
The price is CHF 81 per night
CHF 81
29 Dec - 30 Dec
includes taxes & fees
The free breakfast at Drury Inn & Suites Sikeston, MO gets high marks from our customers. During your stay, you're just a quick walk from City of Miner Convention Center. Features include free WiFi in public areas, free self-parking and a free manager's reception.
Pool
Frühstück inbegriffen

The Farmstead Hotel
778 E 3rd St Caruthersville MO
134.14 km from city centre
The price is CHF 77 per night
CHF 77
22 Jan - 23 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at The Farmstead Hotel. During your stay, you're just a quick walk from Mississippi River. Features include free WiFi in public areas and free self-parking, plus a casino.
Parkplatz inbegriffen
Kostenloses WLAN

Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
73.05 km from city centre
The price is CHF 69 per night
CHF 69
28 Dec - 29 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Drury Inn & Suites Jackson MO. During your stay, you'll be close to Litz Park. Features include free breakfast, free WiFi in public areas and free self-parking.
Pool
Whirlpool

Holiday Inn Poplar Bluff by IHG
2781 N Westwood Blvd Poplar Bluff MO
48.6 km from city centre
The price is CHF 93 per night
CHF 93
2 Jan - 3 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Holiday Inn Poplar Bluff by IHG. During your stay, you'll be within walking distance of Poplar Bluff Regional Medical Center. Features include free WiFi in public areas and free self-parking, plus an indoor pool.
Pool
Haustierfreundlich

Courtyard by Marriott Cape Girardeau Downtown
400 Broadway St. Cape Girardeau MO
80.52 km from city centre
The price is CHF 112 per night
CHF 112
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Courtyard by Marriott Cape Girardeau Downtown. During your stay, you're just a quick walk from Mississippi River. You'll find features such as free WiFi in public areas and free self-parking, plus a restaurant.
Parkplatz inbegriffen
Kostenloses WLAN

Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
75.26 km from city centre
The price is CHF 80 per night
CHF 80
28 Dec - 29 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Drury Inn & Suites Cape Girardeau. During your stay, you'll be within walking distance of Saint Francis Medical Center. Free breakfast, free WiFi in public areas and free self-parking are available.
Pool
Whirlpool

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
75.71 km from city centre
The price is CHF 81 per night
CHF 81
4 Jan - 5 Jan 2026
includes taxes & fees
The free breakfast at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG gets high marks from our customers. During your stay, you'll be within walking distance of Saint Francis Medical Center. You'll find features such as free WiFi in public areas and free self-parking, plus a full-service spa.
Pool
Frühstück inbegriffen

Fairfield Inn & Suites by Marriott Poplar Bluff
3109 Oak Grove Poplar Bluff MO
48.35 km from city centre
The price is CHF 93 per night
CHF 93
18 Jan - 19 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Fairfield Inn & Suites by Marriott Poplar Bluff. During your stay, you're just a quick walk from Poplar Bluff Regional Medical Center. Enjoy features like free breakfast, free WiFi in public areas and free self-parking.
Pool
Frühstück inbegriffen
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southeast Missouri hotels essential information
Accommodation | 620 hotels |
|---|---|
Lowest Price | CHF 48 |
Highest Price | CHF 112 |
Popular hotels | Baymont Inn and Suites by Wyndham Farmington, MO, Drury Plaza Hotel Cape Girardeau Conference Center, The Riverview, Motel 6 Poplar Bluff, MO, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Hampton Inn Sikeston, La Quinta Inn & Suites by Wyndham Festus - St. Louis South, Drury Inn & Suites Sikeston, MO, The Farmstead Hotel, Drury Inn & Suites Jackson MO, Holiday Inn Poplar Bluff by IHG, Courtyard by Marriott Cape Girardeau Downtown, Drury Inn & Suites Cape Girardeau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Fairfield Inn & Suites by Marriott Poplar Bluff |
Recently reviewed Southeast Missouri hotelsebookers verified reviews

Drury Plaza Hotel Cape Girardeau Conference Center
5/5 Excellent
"Wunderschönes Hotel, super Essen und drinks, perfektes Frühstück. Sehr schöne Lage"
A verified traveller stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Posted 3 months ago
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