Southeast Missouri Holiday Homes

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Featured Holiday Homes in Southeast Missouri

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southeast Missouri Holiday Homes essential information

Accommodation
192 Holiday Homes
Lowest Price
CHF 124
Highest Price
CHF 299
Popular accommodation
Unique cabins in the woods
Not friendly for Street Bikes. , “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau, Just A Stone's Throw Cabin from Eminence, Jacks Fork, & Cross County Trail Ride, Unbeatable convenience in amazing Eminence!, Serenity South - Gärten, Flussblick und erfrischender Raum, 3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau, Elegant 3BR in the Heart of Historic Ste Genevieve, Private lake, beach & hot tub, romantic getaway or family vaca, "The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington, Quaint, Beautiful Home next to SEMO and Hospital, Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy, The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO, Bungalow with Hot Tub in Birch Tree, Silo Farm Haus- im Herzen des Weinlandes gelegen!, The Western