Find Cheap Flights from Chicago (CHI) to Panama City (PTY) from CHF 482

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Selected flight deals from Chicago to Panama City

The lowest prices found within the past 7 days from Chicago to Panama City were for one-way flights and CHF 482 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, 26 Jan - Thu, 12 Feb
MDW
Midway Intl.
PTY
Tocumen Intl.
CHF 482 Return, found 17 hours ago
CHF 482
Return
found 17 hours ago
Select Delta flight, departing Mon, 26 Jan from Midway Intl. to Tocumen Intl., returning Thu, 12 Feb, priced at CHF 482 found 17 hours ago
Wed, 31 Dec - Tue, 13 Jan
MDW
Midway Intl.
PTY
Tocumen Intl.
CHF 527 Return, found 17 hours ago
CHF 527
Return
found 17 hours ago
Select Delta flight, departing Wed, 31 Dec from Midway Intl. to Tocumen Intl., returning Tue, 13 Jan, priced at CHF 527 found 17 hours ago
Mon, 26 Jan - Mon, 16 Feb
MDW
Midway Intl.
PTY
Tocumen Intl.
CHF 535 Return, found 17 hours ago
CHF 535
Return
found 17 hours ago
Select Delta flight, departing Mon, 26 Jan from Midway Intl. to Tocumen Intl., returning Mon, 16 Feb, priced at CHF 535 found 17 hours ago
Thu, 15 Jan - Sat, 31 Jan
ORD
O'Hare Intl.
PTY
Tocumen Intl.
CHF 556 Return, found 17 hours ago
CHF 556
Return
found 17 hours ago
Select United flight, departing Thu, 15 Jan from O'Hare Intl. to Tocumen Intl., returning Sat, 31 Jan, priced at CHF 556 found 17 hours ago
Mon, 19 Jan - Mon, 9 Feb
MDW
Midway Intl.
PTY
Tocumen Intl.
CHF 561 Return, found 17 hours ago
CHF 561
Return
found 17 hours ago
Select Delta flight, departing Mon, 19 Jan from Midway Intl. to Tocumen Intl., returning Mon, 9 Feb, priced at CHF 561 found 17 hours ago
Sat, 13 Dec - Wed, 24 Dec
ORD
O'Hare Intl.
PTY
Tocumen Intl.
CHF 570 Return, found 17 hours ago
CHF 570
Return
found 17 hours ago
Select avianca flight, departing Sat, 13 Dec from O'Hare Intl. to Tocumen Intl., returning Wed, 24 Dec, priced at CHF 570 found 17 hours ago
Mon, 26 Jan - Sat, 14 Feb
ORD
O'Hare Intl.
PTY
Tocumen Intl.
CHF 574 Return, found 17 hours ago
CHF 574
Return
found 17 hours ago
Select American Airlines flight, departing Mon, 26 Jan from O'Hare Intl. to Tocumen Intl., returning Sat, 14 Feb, priced at CHF 574 found 17 hours ago
Tue, 9 Dec - Wed, 24 Dec
ORD
O'Hare Intl.
PTY
Tocumen Intl.
CHF 576 Return, found 17 hours ago
CHF 576
Return
found 17 hours ago
Select avianca flight, departing Tue, 9 Dec from O'Hare Intl. to Tocumen Intl., returning Wed, 24 Dec, priced at CHF 576 found 17 hours ago
Tue, 13 Jan - Sat, 31 Jan
ORD
O'Hare Intl.
PTY
Tocumen Intl.
CHF 579 Return, found 17 hours ago
CHF 579
Return
found 17 hours ago
Select avianca flight, departing Tue, 13 Jan from O'Hare Intl. to Tocumen Intl., returning Sat, 31 Jan, priced at CHF 579 found 17 hours ago
Sat, 27 Dec - Sat, 27 Dec
ORD
O'Hare Intl.
PTY
Tocumen Intl.
CHF 2'341 Return, found 11 hours ago
CHF 2'341
Return
found 11 hours ago
Select United flight, departing Sat, 27 Dec from O'Hare Intl. to Tocumen Intl., returning Sat, 27 Dec, priced at CHF 2'341 found 11 hours ago
Cheap Flights from Chicago to Panama City & Flight Information
Origin airport IATA code
MDW
Destination airport IATA code
PTY
Number of flight options
1
Return price
CHF 481
Average flight time
6 hours 27 mins

Best Day to Book Flight from Chicago to Panama City

Panama City Flight Information

Traveling From
Chicago
Origin Airport IATA Code
CHI
Traveling To
Panama City
Destination Airport IATA Code
PTY
Number of Airlines Serving
Available Airlines
Delta, United, avianca, American Airlines
Distance
Direct Flight Time
Flight Price
CHF 482

Need a car after flight from Chicago to Panama City

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

Place to stay after flight from Chicago to Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Panama-Stadt. Freu dich auf inbegriffenes Frühstück, WLAN-Internetzugang (kostenlos) ...
9/10 Wonderful! (4,547 reviews)
Everything

Reviewed on 20 Nov 2025

Opens in a new windowHotel Riu Plaza Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Dieses Hotel mit Wellnessangebot bietet dir einen angenehmen Aufenthalt in Panama-Stadt. Freu dich auf WLAN-Internetzugang (kostenlos), Wellnessbereich und Frühstück ...
8.8/10 Excellent! (1,022 reviews)
Room price is reasonable, location is good!

Reviewed on 24 Nov 2025

Opens in a new windowLas Americas Golden Tower Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Panama-Stadt. Freu dich auf WLAN-Internetzugang (kostenlos), Wellnessbereich und 2 ...
8.8/10 Excellent! (1,003 reviews)
Great service and attention

Reviewed on 17 Nov 2025

Opens in a new windowWaldorf Astoria Panama
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Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Dieses Resort mit 4 Sternen mit Wellnessangebot bietet dir einen angenehmen Aufenthalt in Panama-Stadt. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ...
8.4/10 Very Good! (979 reviews)
Excelente atención y servicio La cuna de bebé era de material como fierro, insegura para bebés que ya se paran un poco El área de juegos de niños siempre mojada y no tenía protección solar podría adecuarse mejor

Reviewed on 1 Nov 2025

Opens in a new windowSheraton Grand Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Panama-Stadt. Freu dich auf inbegriffenes Frühstück, WLAN-Internetzugang (kostenlos) ...
8.4/10 Very Good! (1,216 reviews)
Nice hotel with clean room, wide choice at breakfast buffet. Very clean everywhere. Well located. Will come back.

Reviewed on 19 Nov 2025

Opens in a new windowMegapolis Hotel Panamá
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
Dieses Hotel für Geschäftsreisende bietet dir einen angenehmen Aufenthalt in Panama-Stadt. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service ...
8.8/10 Excellent! (1,557 reviews)
I enjoyed my stay. 6 pillows on the bed is awesome. Nice linens and towels. Clean furniture and kind & helpful staff.

Reviewed on 19 Nov 2025

Opens in a new windowPrincipe Hotel and Suites
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Savings based on all holiday package bookings with Flight + Hotel made on ebookers.ie from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.