Find Cheap Flights from Rome (ROM) to Santiago (SCL) from

Many airlines offer flexible change policies

Earn BONUS+ rewardsOpens in a new window on top of your airline points

Enjoy exclusive promotions on the ebookers app!

Selected flight deals from Rome to Santiago

The lowest prices found within the past 7 days from Rome to Santiago were CHF 689 for one-way flights and for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Cheap Flights from Rome to Santiago & Flight Information
Origin airport IATA code
ROM
Destination airport IATA code
SCL

Santiago Flight Information

Traveling From
Rome
Origin Airport IATA Code
ROM
Traveling To
Santiago
Destination Airport IATA Code
SCL
Number of Airlines Serving
Available Airlines
LATAM Airlines Group, Aerolineas Argentinas, ITA Airways, KLM, Air France, Iberia, British Airways, United, Delta
Distance
Direct Flight Time
Flight Price

Need a car after flight from Rome to Santiago

Place to stay after flight from Rome to Santiago

Holiday Inn Santiago - Airport Terminal by IHG

Holiday Inn Santiago - Airport Terminal by IHG

4 out of 5
Armando Cortinez Norte 2150 Santiago Region Metropolitana
Dieses Hotel für Wintersportler bietet dir einen angenehmen Aufenthalt in Santiago. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
8.8/10 Excellent! (1,417 reviews)
We checked in early. Room clean

Reviewed on 28 Nov 2025

Opens in a new windowHoliday Inn Santiago - Airport Terminal by IHG
Wyndham Santiago Aeropuerto

Wyndham Santiago Aeropuerto

4.5 out of 5
Av. Americo Vespucio 1284 Santiago Santiago
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Santiago. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
9/10 Wonderful! (1,125 reviews)
The hotel is close to the airport. Free parking. The restaurant open until 10.30pm, after that time room service can be reached #620. I didn’t find an option to place my order on-line. Breakfast was not included, we payed for it separately. The price was very reasonable, the food is excellent. The ...

Reviewed on 27 Nov 2025

Opens in a new windowWyndham Santiago Aeropuerto
Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Santiago. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
9.2/10 Wonderful! (929 reviews)
Loved this hotel. It’s like an oasis in the city, with fantastic pool and dining options. We loved it!

Reviewed on 23 Nov 2025

Opens in a new windowMandarin Oriental, Santiago
Save an average of 15% on thousands of hotels when you're signed in
NH Collection Plaza Santiago

NH Collection Plaza Santiago

5 out of 5
Avenida Vitacura 2610 Santiago Region Metropolitana
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Santiago. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
8.6/10 Excellent! (1,004 reviews)
Clean room and great view. Check out was seamless

Reviewed on 30 Nov 2025

Opens in a new windowNH Collection Plaza Santiago
Hotel Capital Bellet

Hotel Capital Bellet

3 out of 5
Saint Paul 1457 / Antonio Bellet 135 Santiago Providencia
Dieses Hotel für Geschäftsreisende bietet dir einen angenehmen Aufenthalt in Santiago. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
9/10 Wonderful! (873 reviews)
Good

Reviewed on 2 Dec 2025

Opens in a new windowHotel Capital Bellet
Ola Santiago Providencia, Tapestry Collection by Hilton

Ola Santiago Providencia, Tapestry Collection by Hilton

4 out of 5
Holanda 307 Santiago
Dieses Hotel bietet dir einen angenehmen Aufenthalt in Santiago. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) und Frühstück ...
9.2/10 Wonderful! (669 reviews)
Staff was great while checking in. Shower worked quite well

Reviewed on 2 Dec 2025

Opens in a new windowOla Santiago Providencia, Tapestry Collection by Hilton
Don't see what you're looking for?
See all available properties in Santiago
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all holiday package bookings with Flight + Hotel made on ebookers.ie from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.