Find Cheap Flights from Madrid (MAD) to Santiago (SCL) from CHF 549

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Selected flight deals from Madrid to Santiago

The lowest prices found within the past 7 days from Madrid to Santiago were CHF 476 for one-way flights and CHF 549 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, 20 Jan - Wed, 4 Feb
MAD
Adolfo Suárez Madrid-Barajas
SCL
Arturo Merino Benitez
CHF 549 Return, found 6 days ago
CHF 549
Return
found 6 days ago
Select Air Canada flight, departing Tue, 20 Jan from Adolfo Suárez Madrid-Barajas to Arturo Merino Benitez, returning Wed, 4 Feb, priced at CHF 549 found 6 days ago
Sat, 24 Jan - Sun, 1 Feb
MAD
Adolfo Suárez Madrid-Barajas
SCL
Arturo Merino Benitez
CHF 663 Return, found 6 days ago
CHF 663
Return
found 6 days ago
Select Delta flight, departing Sat, 24 Jan from Adolfo Suárez Madrid-Barajas to Arturo Merino Benitez, returning Sun, 1 Feb, priced at CHF 663 found 6 days ago
Wed, 21 Jan - Tue, 3 Feb
MAD
Adolfo Suárez Madrid-Barajas
SCL
Arturo Merino Benitez
CHF 689 Return, found 6 days ago
CHF 689
Return
found 6 days ago
Select United flight, departing Wed, 21 Jan from Adolfo Suárez Madrid-Barajas to Arturo Merino Benitez, returning Tue, 3 Feb, priced at CHF 689 found 6 days ago
Thu, 22 Jan - Tue, 3 Feb
MAD
Adolfo Suárez Madrid-Barajas
SCL
Arturo Merino Benitez
CHF 691 Return, found 6 days ago
CHF 691
Return
found 6 days ago
Select United flight, departing Thu, 22 Jan from Adolfo Suárez Madrid-Barajas to Arturo Merino Benitez, returning Tue, 3 Feb, priced at CHF 691 found 6 days ago
Tue, 20 Jan - Sun, 1 Feb
MAD
Adolfo Suárez Madrid-Barajas
SCL
Arturo Merino Benitez
CHF 711 Return, found 6 days ago
CHF 711
Return
found 6 days ago
Select Delta flight, departing Tue, 20 Jan from Adolfo Suárez Madrid-Barajas to Arturo Merino Benitez, returning Sun, 1 Feb, priced at CHF 711 found 6 days ago
Wed, 21 Jan - Thu, 5 Feb
MAD
Adolfo Suárez Madrid-Barajas
SCL
Arturo Merino Benitez
CHF 725 Return, found 6 days ago
CHF 725
Return
found 6 days ago
Select United flight, departing Wed, 21 Jan from Adolfo Suárez Madrid-Barajas to Arturo Merino Benitez, returning Thu, 5 Feb, priced at CHF 725 found 6 days ago
Cheap Flights from Madrid to Santiago & Flight Information
Origin airport IATA code
MAD
Destination airport IATA code
SCL
Number of flight options
1
Return price
CHF 549
Average flight time
9 hours 20 mins

Santiago Flight Information

Traveling From
Madrid
Origin Airport IATA Code
MAD
Traveling To
Santiago
Destination Airport IATA Code
SCL
Number of Airlines Serving
Available Airlines
LATAM Airlines Group, Air Canada, Iberia, avianca, Delta, United, Lufthansa
Distance
Direct Flight Time
Flight Price
CHF 549

Need a car after flight from Madrid to Santiago

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

Place to stay after flight from Madrid to Santiago

Holiday Inn Santiago - Airport Terminal by IHG

Holiday Inn Santiago - Airport Terminal by IHG

4 out of 5
Armando Cortinez Norte 2150 Santiago Region Metropolitana
Dieses Hotel für Wintersportler bietet dir einen angenehmen Aufenthalt in Santiago. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
8.8/10 Excellent! (1,417 reviews)
We checked in early. Room clean

Reviewed on 28 Nov 2025

Opens in a new windowHoliday Inn Santiago - Airport Terminal by IHG
Wyndham Santiago Aeropuerto

Wyndham Santiago Aeropuerto

4.5 out of 5
Av. Americo Vespucio 1284 Santiago Santiago
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Santiago. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
9/10 Wonderful! (1,113 reviews)
Modern hotel with nice rooms similar to what you would find in Canada or the States. Tip for shuttle service: it comes to the departures level, not arrivals. It comes 15 minutes after the hour. Once I figured that out I no longer had to take Über.

Reviewed on 22 Nov 2025

Opens in a new windowWyndham Santiago Aeropuerto
Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
Dieses Hotel im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Santiago. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
9.2/10 Wonderful! (926 reviews)
Loved this hotel. It’s like an oasis in the city, with fantastic pool and dining options. We loved it!

Reviewed on 23 Nov 2025

Opens in a new windowMandarin Oriental, Santiago
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Hotel Capital Bellet

Hotel Capital Bellet

3 out of 5
Saint Paul 1457 / Antonio Bellet 135 Santiago Providencia
Dieses Hotel für Geschäftsreisende bietet dir einen angenehmen Aufenthalt in Santiago. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) ...
9/10 Wonderful! (862 reviews)
The room was very nice and the breakfast was very good

Reviewed on 27 Nov 2025

Opens in a new windowHotel Capital Bellet
Ola Santiago Providencia, Tapestry Collection by Hilton

Ola Santiago Providencia, Tapestry Collection by Hilton

4 out of 5
Holanda 307 Santiago
Dieses Hotel bietet dir einen angenehmen Aufenthalt in Santiago. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) und Frühstück ...
9.2/10 Wonderful! (663 reviews)
Room was clean. Common areas great. Staff very pleasant and helpful. Light problem fixed immediately. Missing soap took two calls. Nice neighborhood with some great restaurants.

Reviewed on 25 Nov 2025

Opens in a new windowOla Santiago Providencia, Tapestry Collection by Hilton
DoubleTree by Hilton Hotel Santiago - Vitacura

DoubleTree by Hilton Hotel Santiago - Vitacura

4 out of 5
Avenida Vitacura 2727, Las Condes Santiago
Dieses Hotel bietet dir einen angenehmen Aufenthalt in Santiago. Freu dich auf WLAN-Internetzugang (kostenlos), Parken ohne Service (kostenlos) und Frühstück ...
9.2/10 Wonderful! (1,007 reviews)
Everything good but the room was too noisy.

Reviewed on 22 Nov 2025

Opens in a new windowDoubleTree by Hilton Hotel Santiago - Vitacura
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Savings based on all holiday package bookings with Flight + Hotel made on ebookers.ie from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.