My son and his friend were attending the Star Wars conference at ExCel and I had business with an art gallery on Brick Lane, so this place really suited our needs for our first week in England.
It's right next to the Poplar train station, so it was easy to get anywhere else. It might be too far away if you have things to do more centrally located in London, but it was perfect for our needs.
We also discovered two restaurants nearby that were by far our most favorite places to eat during our entire two week stay in the UK.