Find Cheap Flights from Madrid (MAD) to Brussels (BRU) from CHF 166

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Selected flight deals from Madrid to Brussels

The lowest prices found within the past 7 days from Madrid to Brussels were CHF 82 for one-way flights and CHF 166 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Cheap Flights from Madrid to Brussels & Flight Information
Origin airport IATA code
MAD
Destination airport IATA code
BRU
Number of flight options
1
Return price
CHF 165
Average flight time
2 hours 18 mins

Brussels Flight Information

Traveling From
Madrid
Origin Airport IATA Code
MAD
Traveling To
Brussels
Destination Airport IATA Code
BRU
Number of Airlines Serving
Available Airlines
TAP Portugal, Brussels Airlines, Iberia, KLM
Distance
Direct Flight Time
Flight Price
CHF 166

Need a car after flight from Madrid to Brussels

Lowest prices found within the past 4 days. Prices and availability subject to change. Additional terms may apply.

Place to stay after flight from Madrid to Brussels

The Hotel

The Hotel

5 out of 5
38 Boulevard de Waterloo, Brussels
Dieses Hotel mit 5 Sternen im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Brüssel. Freu dich auf WLAN-Internetzugang (kostenlos), Wellnessbereich ...
8.8/10 Excellent! (1,294 reviews)
"We enjoyed our room and had a great experience using the hotel spa. We had a not so great experience at the bar. The service was incredibly slow and when we finally got our drinks they brought a white wine when I had ordered a red. Otherwise this was a great location"

Reviewed on 2 Oct 2025

Opens in a new windowThe Hotel
Thon Hotel Brussels City Centre

Thon Hotel Brussels City Centre

4 out of 5
Avenue du Boulevard 17, Brussels
Dieses Hotel mit 4 Sternen für Familien bietet dir einen angenehmen Aufenthalt in Brüssel. Freu dich auf WLAN-Internetzugang (kostenlos), Frühstück (gegen Gebühr) ...
8.6/10 Excellent! (1,017 reviews)
"Overall good stay"

Reviewed on 1 Oct 2025

Opens in a new windowThon Hotel Brussels City Centre
Warwick Grand-Place Brussels

Warwick Grand-Place Brussels

4 out of 5
Rue Duquesnoy 5-7, Brussels
Dieses Hotel mit 4 Sternen für Familien bietet dir einen angenehmen Aufenthalt in Brüssel. Freu dich auf WLAN-Internetzugang (kostenlos), Frühstück (gegen Gebühr) ...
8.6/10 Excellent! (1,528 reviews)
"It was a perfect location for, as we like to walk a lot to really get a sense of another country's culture. Safe, clean, easily accessible to many venues."

Reviewed on 28 Sept 2025

Opens in a new windowWarwick Grand-Place Brussels
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Pullman Brussels Centre Midi

Pullman Brussels Centre Midi

4.5 out of 5
Place Victor Horta 1, Brussels
Dieses Hotel mit 4,5 Sternen im luxuriösen Stil bietet dir einen angenehmen Aufenthalt in Brüssel. Freu dich auf WLAN-Internetzugang (kostenlos), Wellnessbereich ...
8.6/10 Excellent! (1,004 reviews)
"The staff was great at all points"

Reviewed on 3 Oct 2025

Opens in a new windowPullman Brussels Centre Midi
a&o Brussel Centrum

a&o Brussel Centrum

2 out of 5
Blvd. du Roi Albert II, 44, Brussels
Dieses Hotel bietet dir einen angenehmen Aufenthalt in Brüssel. Freu dich auf WLAN-Internetzugang (kostenlos), Frühstück (gegen Gebühr) und Parken ohne Service ...
7.8/10 Good! (1,001 reviews)
"Excellent"

Reviewed on 28 Sept 2025

Opens in a new windowa&o Brussel Centrum
Citybox Brussels

Citybox Brussels

3 out of 5
Rue Dejoncker 53, Brussels, Bruxelles
Dieses Hotel mit 3 Sternen bietet dir einen angenehmen Aufenthalt in Brüssel. Freu dich auf WLAN-Internetzugang (kostenlos), eine rund um die Uhr besetzte Rezeption ...
8.6/10 Excellent! (576 reviews)
"Easy check in, basic but clean and comfortable room. Metro options nearby. Good price."

Reviewed on 4 Oct 2025

Opens in a new windowCitybox Brussels
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all holiday package bookings with Flight + Hotel made on ebookers.ie from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.